mercredi 17 décembre 2008
mercredi 8 octobre 2008
2008 Medicine Nobel prize winner Luc Montagnier relating Perez's DNA supracode discovery
from the SCIENCE et AVENIR April 1995 paper entitled "La Musique des genes" (The music of genes)
in reserchs with 2 of the 3 co-discoverers of HIV virus:
Professor Jean-claude Chermann
and Professor Luc Montagnier (see his 2008 NOBEL video lecture)...
more details on:
Both researchers were very open and passionned facing the J.C. Perez "DNA SUPRACODE" discovery..."Passion" and "to be open to new interdisciplinary ways"... Here are two central qualities of great researchers...
le professeur jean-claude Chermann ([[INSERM]], 1992 et 1993)... a écrit:
Laurence Espagnolle, 'l'ère des savanturiers', relate l'avis du co-découvreur du Sida Jean-claude Chermann à propos de la découverte de jean-claude Perez dans le mensuel économique 'Objectif Mediterranée', numéro 9, mai 1993 '(.../...Nous avons fait travailler Jean-claude Perez sur des expériences que nous avions déjà faites. Il est rapidement tombé sur une zone importante du virus VIH que nous avions mis quatre ans à trouver .../... )'
"We suggested with Jean-Claude Perez working on experiments which we had already made. He quickly fell on an important area within the HIV1 virus which we had spent four years to find".
Professor Jean-claude CHERMANN,
Co-discoverer of the AIDS virus - INSERM - Marseille -
In "Objectif Mediterranée" French economic magazine
May 1993
relating J.C. Chermann and Luc Montagnier HIV co-discoverers...
in french on FACEBOOK:
Dans FACEBOOK "Comité de soutien pour élargir le prix Nobel de médecine au Pr Chermann", Jean-claude Perez a écrit:
"Vers 1993, j'eus l'immense privilège de de proposer d'une part à Jean-claude Chermann, d'autre part à Luc Montagnier d'appliquer à leurs recherches sur HIV ma découverte d'un "supracode de l'ADN", découverte mathématique, qui montrait l'adn des génomes HIV sous un éclairage totalement nouveau et inédit...
http://golden-ratio-in-dna.blogspot.com/2008/10/2008-medicine-nobel-prize-winner-luc.html
Il s'en suivit deux partenariats entre mon lilliputien labo start up PRIVE GeNum et l'INSERM d'une part (Chermann) et la FMPRS (Montagnier) d'autre part.
Nous avons obtenu dans les 2 cas des résultats et avancées potentielles remarquables.
Hélas mon petit labo aux "pieds financiers d'argile" mourut avant terme...
dans les 2 cas j'ai rencontré deux chercheurs
1/ OUVERTS aux idées nouvelles venant d'une autre discipline (ici les maths)
2/ PASSIONNES et HUMAINS
3/loin de ces chercheurs aparatchics d'appareils et de castes.
Au delà de "NOBEL OR NOT NOBEL" c'est à celà que l'on reconnait les TRES grands et véritables chercheurs...
Tant CHERMANN que MONTAGNIER sont de tels très grands chercheurs...
Et croyez-moi, ils ne sont point majorité dans l'univers de la recherche..."
vendredi 1 août 2008
Who is Jean-claude PEREZ ???
1/ Summary...
Jean-claude perez summary:
publications...
Studying numerical patterns and structures within DNA and whole genomes since 1990 years: ["order and chaos in DNA" in KIBERNETES 1992] ( http://golden-ratio-in-dna.blogspot.fr/2008/01/1992-order-and-chaos-in-dnathe-denis.html and http://golden-ratio-in-dna.blogspot.fr/2008/01/1991-first-publication-related-to.html )
last publications summary:
2010: http://www.ncbi.nlm.nih.gov/pubmed/20658335 paper in INTERDISCIPLINARY SCIENCE (China)(chairman Pr Luc Montagnier) : Interdiscip Sci Comput Life Sci (2010) 2: 228–240DOI: 10.1007/s12539-010-0022-0 Codon Populations in Single-stranded Whole Human Genome DNA Are Fractal and Fine-tuned by the Golden Ratio 1.618
2011: http://www.bitlifesciences.com/wcv2011/fullprogram_track2.asp http://www.scribd.com/doc/57828784/jcperezBeijing032011 support Pr Luc Montagnier FMPRS World AIDSFoundation UNESCO ( Fondation mondiale prévention et recherche SIDA ) and Jean-René Fourtou Vivendi Universal chairman
June 2012: publication in "The Cerebellum" : with Dr Andras Pellionisz (silicon valley) "RECURSIVE GENOME FUNCTION OF THE CEREBELLUM: GEOMETRIC UNIFICATION OF NEUROSCIENCES AND GENOMICS"
more: for your information, on the future of biomathematics... please visit:
http://golden-ratio-in-dna.blogspot.com/ https://sites.google.com/site/codexbiogenesis/home http://www.amazon.fr/gp/reader/2874340448/ref=sr_1_1?p=S039&keywords=codex+biogenesis&ie=UTF8&qid=1313340531 http://www.scribd.com/jean_claude_perez/documents
5 Books on artificail neural networks, GMO risk, and Biomathematics, particularly: "CODEX BIOGENESIS" (2009)
detailed biography here
You could also join Jean-claude Perez on FACEBOOK...
An engineer and French scholar from Bordeaux university, Perez worked principally in IBM in both areas of Biomathematics and artificial intelligence (see: Teuvo Kohonen book) particularly in artificial neural networks with his holographic-like (see page 1111 in Karl Pribram's book) self-organization model entitled "fractal chaos" issued from both theories of chaos of Ilya Prigogine and autopoiesis of Francisco Varela).
In this last area, with the "DNA supracode", he proove that DNA coding for genes is structured by golden ratio and Fibonacci numbers related proportions . He verify particularly this discovery in the field of HIV genome by partnerships with Professor Luc Montagnier, the 2008 Nobel prize in Physiology or Medicine, co-discoverer of HIV virus. Then he worked about 10 years in the field of whole genomes analysis
French Full Biography:
Peter Marcer, Kybernetes, ''Order and chaos in DNA―the Denis Guichard Prizewinner : Jean-Claude Perez'', Kybernetes ISSN 0368-492X [http://cat.inist.fr/?aMode
1992: Peter Marcer, KYBERNETES (revue de BCS: British Computer Society), ''"order and chaos in DNA"'' jc Perez the Denis Guichard prizewinner http://golden-ratio-in-dna
J.C. Perez, ''Fractal Chaos: a new neural network holographic model'', International Neural Networks Society (INNS) conference Boston USA in NEURAL NETWORKS international publication, 1988.
J.M. Bertille, J.C. Perez, ''« A spatio temporal novelty detector using FRACTAL CHAOS model »'', IJCNN conference, Washington, 1990, published by NEURAL NETWORKS (INNS).
J.C. Perez, Jerry Magnan, J.M. Bertille, « Global optimization with a lattice dynamic system », SIAM dynamic systems conference, Orlando USA, 1990.
Gonzalo Casino, ''"Chips con sentido comun, los ordenadores neuronales consiguen modelizar la inteligencia"'', enviado especial Lyon, quotidien espagnol Diario 16, domingo 18 marso 1990, pages 1 et 2 "Sciencias"
Jacques de Schryver, ''"Entretiens d Lyon: pleins feux sur l'informatique neuronale"'', magazine Minis et Micros, 26 mars 1990, relate la conférence invitée de J.C. Perez ''"Digital hologram computers"'' à la conférence internationale des "entretiens de Lyon" le 7 mars 1990 (voir référence au paragraphe ouvrages collectifs)
J.C. Perez, « Le langage caché de l'ADN: vers une nouvelle théorie du "chaos discret" ou de "l'ordre par fluctuations discrètes" », deux conférences initiées par Ilya Prigogine à l'Institut des congrès Solvay de l'ULB, Bruxelles, 1991 puis 20 juillet 1993.
J.C Perez, « The Global Language of DNA », HGM93, Human Genome mapping workshop 1993, ( projet Hugo ), 1993, Kobe Japon.
J.C. Perez, HUGO conference Edimbourg 2001, [http://hgm2001.hugo-intern
C'est Luc Montagnier, Prix Nobel de Médecine 2008, qui suggéra ce nom de "supracode de l'adn"
Luc Montagnier, ''L'avis sur la découverte de J.C. Perez par Luc Montagnier'' publié dans l'article de ''Sciences et Avenir'' sus-cité « la musique des gènes » (avril 1995) voici des extraits de son avis sur une demi page de l'article: ''.../... le principe de la découverte de jean-claude perez m'intéresse, il est très possible que par delà les séquences, une sorte de ''"supracode de l'ADN"'' existe.../...Cela étant, j'encourage le mathématicien à continuer ses recherches et à valider ses travaux, il aimerait aujourd'hui relier la virulence du virus à des différences de séquences.../...'' Les résultats de cette suggestion de collaboration pour validation sont totalement décrits dans le livre "l'ADN décrypté".
Le texte intégral de l'avis sur la découverte de J.C. Perez par Luc Montagnier publié dans l'article de ''Sciences et Avenir'' sus-cité « la musique des gènes » (avril 1995)cette expression de ''« supracode de l'ADN »'' dans l'article ''« la musique des gènes »'', dédié à la découverte de Jean-Claude Perez, publié dans ''Sciences et Avenir''.
...Dans le « supracode de l'ADN », se forment des milliers de structures numériques (baptisées ''« résonances »'') entre les proportions relatives de nucléotides suivant la suite de Fibonacci et la suite de Lucas.
...et d'une harmonie...
* la spécialiste Italienne du SYMBOLISME Maria Grazia Lopardi in Architettura sacra medievale. Mito e geometria degli archetipi
mardi 15 juillet 2008
mardi 27 mai 2008
Origins of Life GOLDEN HOLE Strange Attractor
The image of black holes is often used to explain the origin of the universe and galaxies.
Here, I'll use the analogy of the golden hole to demonstrate clearly a kind of fatalism, strange attractor, which is a prerequisite to any form of life.
This demonstration, extracted from the end of my 2008 running book "codex biogenesis: the book of 13 codes of DNA" is based on this strange discovery of "the equation of life."
A brief explanation of the graph:
In each of the 3 curves, the central point is the exact average atomic mass while 2 points side correspond to an artificial "noise", a disruption of + / - 0.01% (1 / 10000) of the same real average atomic mass.
On the other hand, each of the 3 curves correspond to different levels or stages of a possible life:
-- The BLUE curve in the background is related to primitive molecules of organic isotopes measured in interstellar clouds (interstellar dust clouds).
-- The GREEN middle curve corresponds to 5000 combinations of organic molecules parity N + H = pair, generated randomly (example: in NH3: N + H3 = 4).
-- Finally, the RED curve forefront corresponds to the averages atomic masses related to the 18 amino acids constructed from CONH bioatoms (excluding CYS here and MET which contain sulfur atoms).
In this chart it is obvious that the more we advance towards molecules present on earth, and "the equation of life" projection becomes pointed and selective, this optimal balance being hyper-sensitive to the slightest disturbance…
Asked to follow:
"Are there on Mars or Titan such perfect balances corresponding to the average atomic mass observed on Earth (pachwork isotopes measured on earth: example O16, O17, and O18 balance)? "
to follow
.../...
jeudi 10 avril 2008
Is There an "EQUATION of LIFE" ? ? ?
"Is there an EQUATION of LIFE?"
INTRODUCTION:
”Are there any difference between the" bio-atoms "- atoms involved in the biology of life - such as carbon, nitrogen, hydrogen or oxygen and all other atoms from the periodic table of Mendeleëv, who do not contribute so essential to life, such as titanium, lead, cobalt or lanthanides?”
An analysis that is based only on their common denominator - their atomic weight - could perhaps be a valuable starting point for any researcher attempting to address this critical issue.
The law entitled the "equation of life" - because we could not baptize it with another title - which will now be presented should provide a response consistent with this big question…
Not only does this law will distinguish between CONHSP bio-atoms - the main building “blocks of life” - and the remaining population of all other atoms, but also by providing an uniform and regular numerical scale of integer numbers common to these 6 bio-atoms, to the UTCAG nucleotides of RNA and DNA, and to the 20 amino acids, then this law will allow the UNIFICATION of the 3 "languages" of biology that are DNA, RNA and amino acids.
Then this "common" numerical scale, this "Numerical CODE" will bring unknown new levels of organizations and structures, "meta-levels", kinds of "meta-codes" or "meta-languages" organizing at a large scale all biological structures, genes and whole genomes.
So, finally, I must also confess now that this famous discovered new law is based on two universal constants: the first well-known, "Pi", and the other, more controversial, and generally for discussion: "Phi the Golden ratio” …
more on the book CODEX BIOGENESIS
mardi 25 mars 2008
mercredi 27 février 2008
2008: The "EQUATION of LIFE"
Like ARTS
(paul Klee "Cat and Bird" 1928...) http://www.moma.org/collection/browse_results.php?criteria=O%3AAD%3AE%3A3130&page_number=52&template_id=1&sort_order=1
... LIFE also as UNDERGROUND LAWS and RULES... (*)
Both Keys of HARMONY
(*) 2 and Phi=1.618 are both keys of PROPORTIONS in Paul Klee's CAT EYES and HUMAN Genome Codons Populations MODELLING (CODEX BIOGENESIS chapter 19)
No comment...
vendredi 22 février 2008
2009: CODEX BIOGENESIS book to be published (October 2009)
CODEX BIOGENESIS: octobre 2009
==============================
available on AMAZON
available on DG livres
available on FNAC
available on RESURGENCE Editions
==============================
CONTENTS:
Avant-propos
Préambule
Préface de l'auteur
Préface de Carl Johan Calleman (original English Foreword available on-line)
Traduction de la préface
Introduction
Résumés des 20 chapitres
Partie 1 : « Premiers SOUPÇONS … »
Chapitre 1 : 1er CODE – Le Nombre « 13 »
jaillit du génome humain
Chapitre 2 : Le Nombre « 2 » contrôle la Nature :
l’équation de la table périodique des Éléments de Mendeleïev
Chapitre 3 : Une « onde fossile » de période « 3 »
vibre dans l’ADN de tous les gènes
Chapitre 4 : L’évidence d’une Asymétrie « CG » dans tout
le génome humain
Partie II : « Premières PREUVES … du Génome vers l’Atome »
Chapitre 5 : 2d CODE – Le Nombre « 2 » et le rapport numérique
des « 2/3 » partagent la population des 64 codons
du génome humain
Chapitre 6 : 3e CODE – La Symétrie miroir des « codons jumeaux »
Chapitre 7 : L’asymétrie miroir des « codons jumeaux »
Chapitre 8 : Dichotomies de codes gigognes et emboîtés
Chapitre 9 : 4e CODE – Le « Code Numérique », entre Nombres
entiers et Symboles : le « Code de la Paix » ou « Peace Symbol »
règne sur le génome humain
Chapitre 10 : 5e CODE – Le « Code Harmonique » des octaves
harmoniques
Chapitre 11 : Phi2/10, carré du Nombre d’or, organise les
proportions et les masses atomiques des populations de codons
Chapitre 12 – L’équilibre parfait des masses atomiques des
2 brins d’ADN du génome humain
Chapitre 13 : L’hypothétique existence d’un « HomOGM » à
chromosomes YY
Chapitre 14 : La Symétrie des « codons jumeaux » insensible
à l’infinie diversité humaine des SNP
Chapitre 15 : 6e CODE : Le ratio 8/5, tuning parfait des 8 derniers
codons jumeaux CG
Chapitre 16 : « MATRIX » : les codes de pliage du
« dragon humain »
Chapitre 17 : L’homme et le chimpanzé : plutôt frères que cousins
Chapitre 18 : Évidence de 2 ancêtres chromosomiques
communs à l’homme et au chimpanzé
Chapitre 19 : 7e CODE : le code génomique révèle les deux
Nombres génériques du génome humain : 2 et Phi
Chapitre 20 : Le 8e CODE – L’ÉQUILIBRE des populations
d’ISOTOPES, « souffle premier de la Vie » …
ou un coin du voile dévoile le 13e CODE : « L’Equation of Life
(PI-masse) » projection, véritable « E=mc2 de la Biologie »
Épilogue
Postface
Annexe 1 : « The Life Code » : Théorie Unifiée de l’Information
Génétique : « Le Code Génétique Angulaire Universel »
Annexe 2 : Conséquences décisives dans le débat « faussé » sur
le risque des OGM
Bibliographie
dimanche 10 février 2008
1988: "CLOWN-like" pattern then Holographic Memory emerges from Fractal Chaos
When a "CLOWN-like" pattern emerges spontaneously from the CONWAY's cellular automata...
At ORIGINS of my research trip, at the end of "SEVENTIES" years, I was discovering power of basic primitive SELF-ORGANIZATION from primitive cellular automata...
I had the idea to run the famous "GAME of LIFE" of John Conway running -at the end of SEVENTIES - on large IBM computers... and on large 2-dimensions binary array spaces (100x100 digits was, at this computers story time, a very big Conway's cellular space...)
The famous Martin Gardner's paper in Scietific American:
More on Conway's cellular automata on WIKIPEDIA...
Here (step1) an initial full randomly distributed "white noise"... produces (step2)... basic differentied high level organic cells...
Sometimes (step3) this small 7 binary cells "U letter" could emerge from chaos...
Then, if it has a sufficient 2-D space to propagates, it becomes (step4) a butterfly-like pattern then spontaneously this "CLOWN-like" pattern...
and finally an organic bistable flip-flop complex pattern like a kind of virtual human head bone-based skeleton!!!
OH LA LA !!! My (maths self-organization) God!
Then I had the idea to replace in the network each basic binary cell by the more complex virtual mathematical cell: a FRACTAL...
My neural networks model "FRACTAL CHAOS" was born...
http://www.ellipse.ch/Produit.aspx?Produit=81929
Fractal Chaos by the american neurobiologist karl H. Pribram in his book "brain and perception":
- Pribram, Karl (1991). Brain and perception: holonomy and structure in figural processing. Hillsdale, N. J.: Lawrence Erlbaum Associates. ISBN 0898599954. https://books.google.fr/books/about/Brain_and_Perception.html?hl=fr&id=uImqkVSJqIAC&redir_esc=y
Please clic to zoom it...
http://ieeexplore.ieee.org/Xplore/login.jsp?url=/iel2/148/3745/00137678.pdf?arnumber=137678
1990: From FRACTAL CHAOS to GOLDEN RATIO
Please click on the image to zoom it...
http://ieeexplore.ieee.org/xpl/freeabs_all.jsp?arnumber=137678
Integers neural network systems (INNS) using resonance propertiesof a Fibonacci's chaotic `golden neuron'
Perez, J.-C.
IBM, Montpellier;
This paper appears in: Neural Networks, 1990., 1990 IJCNN International Joint Conference on
Publication Date: 17-21 Jun 1990
On page(s): 859-865 vol.1
Meeting Date: 06/17/1990 - 06/21/1990
Location: San Diego, CA, USA
References Cited: 10
INSPEC Accession Number: 3926657
Digital Object Identifier: 10.1109/IJCNN.1990.137678
Posted online: 2002-08-06 17:16:55.0
Abstract
Original neural network research which results from the intersection of chaos theory and number theory is presented. The chaos theory background stems from the fractal chaos neural network model, and the number theory background stems from particular selective sensitivity emerging from neurons based on Fibonacci's integer number settings. In fact, there is a mutual reinforcement between numerical holographic-like properties related to the fractal chaos network and to numbers deduced from the golden ratio. The dynamics of the fractal chaos model are limited to a subset of particular initial and control settings related to the golden ratio and Fibonacci's integer numbers. An analysis is made of ultrasensitive and selective capabilities of Fibonacci's neuron. This model anticipates potential perspectives in the neural networks field
jeudi 24 janvier 2008
1997: The Mendeleiev Periodic Table Predictive Equation
se also in Belgrade University web site http://www.mi.sanu.ac.rs/vismath/perez2009/perez.pdf:
The Perez’s Generic Predictive Equation
of Mendeleiev’s Periodic Table
“Are there Numbers in the Nature?” Let us take the example of the famous table of Mendeleev, no one never had the idea to seek a possible mathematical law which would organize the information and the structure of "the most heterogeneous table of Science".
Jean-claude perez discovered this law: the equation of the periodic table of Mendeleev. Here is a short summary: Pionnering in research of numbers in DNA, this researcher was questionning about possible DIFFERENCIATION between life based Elements (carbon oxygen etc) and all others (aluminium, copper etc). In fact, he discovered the exact contrary: a law of UNIFICATION of all Elements of Nature... Then he discovered a very simple equation which generates and predicts the structure of the table of Mendeleev.
-This equation predicts the number of elements of any layer of period "p" in the table according to the only value of this period "p". Beyond this mathematical modeling of the periodic table of the Elements,
-This equation underlines, in its formulation, the " trace" of the 4 fundamental quantum Numbers.
-This modeling predicts the structure of the hypothetical extensions of the table of Mendeleev towards possible Eléments (real) unknown which would be located beyond the last known radioactive Elements.
-This modeling also makes it possible to imagine an infinity of other Elements (virtual) which one could however predict positioning towards the low layers of the table, like their quantum properties.
To summarize, IF:
-c(p) a horizontal layer of elements of the table of Mendeleev,
-"p" the period associated with this c(p) layer such as p = [ 1 2 3 4 5 6 7 … ],
-Int(v) the whole part of the numerical value "v". exp: if v=2.35,then Int(2.35)=2.
THEN: one obtains c(p), the number of elements contained in the c(p) layer of order p, by applying the formula:
c(p) = 2 [Int ((p+2) /2 )]*2
Examples :
If p=1 then c(1)=2
If p=2 then c(2)=8 If p=3 then c(3)=8
If p=4 then c(4)=18 If p=5 then c(5)=18
If p=6 then c(6)=32 If p=7 then c(7)=32
If p=8 then c(8)=50 If p=9 then c(9)=50
…/… If p=16 then c(16)=162
To conclude : -1- The periodic table of the Elements is modélisable. It is structured by a numerical structure of whole numbers. -2- This structure is deterministic and predictive, then, for any period p, it can be calculated by applying "the Perez's generic equation of Mendeleev". -3- The generic equation is completely controled by the four quantum Numbers. -4-This generic equation makes it possible to check the regularity of the common table of Mendeleev, but it can also "predict" and anticipate the existence of hypothetical Eléments now unknown, of which it makes it possible to determine the quantum properties, then electronic and chemical hypothetical properties.
Please see a detailed paper zooming text image at the top of this paragraph...
mercredi 23 janvier 2008
1994: The First Music of Genes
Evolution from a fossil charançon towards drosophile
and
music of the KIRAS ONNCOGENE...
Please clic on images to zoom...
Facing this image of dynamics of DNA supracode resonances, I had immediately the intuition to show this pattern on another support: MUSIC...
Then, to explore both aesthetics dimension of this discovery, Perez published in 1994 an audio CD entitled
So, now, if you CLIC on the following text...
"The First Music Of Genes" (Introduction, track 1)
Then you enter in the AUDIO CD Introduction track of - SACEM GEN0694 - (a subset of supracode for the oncogene KIRAS involved in cancers)...
Now a dedicaced GOOGLE WEB SITE is available here... its name: TheFirstMusicOfGenes
mardi 22 janvier 2008
1992: Order and chaos in DNA―the Denis Guichard Prizewinner : Jean-Claude Perez
About strong links
between FRACTALS and FIBONACCI NUMBERS:
In the Perez's fractal from fractal chaos model, the central focusing region is...the GOLDEN RATIO attractor, then, in its immediate close neighbooring, are the consecutive FIBONACCI NUMBERS ratios !!! (please zoom on the fractal photo to magnify it)
"From Golden Ratio in Fractal Chaos towards Golden Ratio in DNA..."
1992: Peter Marcer in KYBERNETES Magazine:
References of the publication:
Please do a zoom on the 2 pages text...
lundi 21 janvier 2008
1995: Ethics of a discovery: jean-claude perez's french video of 1995 about DNA supracode
A french video describing the "DNA SUPRACODE" by jean-claude Perez...
www.terre.tv/indexvod.php?case=1&ref=00068
More related to ETHICS (in French, from book "l'ADN décrypté"):
vendredi 18 janvier 2008
1991: The First publication related to GOLDEN RATIO within DNA sequences
Please, click on images to zoom them!
The first english paper relating Fibonacci/Lucas TCAG nucleotides proportions was the following:
J.C. Perez - "Chaos DNA and Neuro-computers : a golden link / The hidden language of genes, global language and ordre in the human genome", in Speculations in Science and Technology, vol 14 number 4 1991, ISSN 0155-7785.