October 2013 APPLIED MATHEMATICS
(special issue BIOMATHEMATICS)
The “3 Genomic Numbers” discovery:
(special issue BIOMATHEMATICS)
The “3 Genomic Numbers” discovery:
How our genome single-stranded DNA sequence
is “self-designed” as a numerical whole
Jean-claude Perez
Email: jeanclaudeperez2@gmail.com
Received May 22, 2013; revised June 10, 2013; accepted June 14, 2013
===============================Note:
All results presented in this article are REPRODUCIBLE by other researchers from the following basic information:
[3] International Human Genome Project Sequencing Centers
and Verified by NCBI and UCSC, “Human Genome Finalized
BUILD34. Build 34 Finished Human Genome
Assembly,” 2003.
http://genome.ucsc.edu/FAQ/FAQreleases.html
and
Table 3 of the article pp 40.
===============================
The article is now available in OPEN ACCESS on line:
details access:
access:
from SCIRP scientific research APPLIED MATHEMAICS website http://www.scirp.org/
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The “3 Genomic Numbers” discovery:
How our genome single-stranded DNA sequence
is “self-designed”
as a numerical whole
Copyright © 2013 Jean-claude Perez. This is an
open access article distributed under the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium,
provided the original work is properly cited.
"The beginning
(1) is the middle (2) of the whole (Phi)"
Here is my interpretation of this famous
sentence from Pythagoras[2]...
Abstract
This article proves the
existence of a hyper-precise global numerical meta-architecture unifying,
structuring, binding and controlling the billion triplet codons comprising the
sequence of single-stranded DNA of the entire human genome. Beyond the
evolution and erratic mutations like transposons within the genome, it's as if
the memory of a fossil genome with multiple symmetries persists. This recalls
the "intermingling" of information characterizing the fractal
universe of chaos theory. The result leads to a balanced and perfect tuning between
the masses of the two strands of the huge DNA molecule that constitute our
genome. We show here how codon populations forming the single-stranded DNA
sequences can constitute a critical approach to the understanding of junk DNA
function. Then, we suggest revisiting certain methods published in our 2009
book “Codex Biogenesis”. In fact, we demonstrate here how the universal genetic
code table is a powerful analytical filter to characterize single-stranded DNA
sequences constituting chromosomes and genomes. We can then show that any genomic
DNA sequence is featured by three numbers, that characterize it and its
64 codon populations with correlations greater than 99%. The number
"1" is common to all sequences, expressing the second law of Chargaff.
The other 2 numbers are related to each specific DNA sequence case
characterizing life species. For example, the entire human genome is
characterized by three remarkable numbers 1, 2, and Phi = 1.618 the golden
ratio. Associated with each of these three numbers, we can match three axes of
symmetry, then "imagine" a kind of hyperspace formed by these codon
populations. Then we revisit the value
(3-Phi) / 2 which is probably universal and common to both the scale of quarks
and atomic levels, balancing and tuning the whole human genome codon population.
Finally, we demonstrate a new kind of duality between “form and substance” overlapping the whole human genome : we will show that - simultaneously
with the duality between genes and junk DNA - there is a second layer of
embedded hidden structure overlapping all the DNA of the whole human genome,
dividing it into a second type of duality information / redundancy involving golden ratio proportions.
Keywords : genetic code; codon
populations; junk DNA; cancer genomics chromosomal translocations; genomes
diversity; chromosomes diversity; whole human genome DNA sequence; “Phi” the
golden ratio; Fibonacci numbers; information theory; symmetry; cellular automata; Chargaff’s codon level symmetry principle; fractal
self-similarity; “e” Euler's number; “Pi”; form and substance; redundancy; encryption.
[1]
This article publishing was supported by Professor Luc Montagnier, Fondation Mondiale Recherche et Prévention SIDA
This article publishing was supported by Professor Luc Montagnier, Fondation Mondiale Recherche et Prévention SIDA
[2] “1”,
”2” and “Phi the golden ratio” are the 3 genomic numbers characterizing codon
populations of the whole human genome.
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http://fr.scribd.com/doc/169323556/7401586of18september2013
published 4 october 2013 in open access by http://www.scirp.org/journal/am/
10B access
